麻疹病毒IgG ELISA检测试剂盒

英文名称：Measles virus IgG enzyme-linked immunosorbent assay kit

广州健仑生物科技有限公司

（广州健仑生物科技有限公司是集研制开发、销售、服务于一体的优良企业,公司产品涉及临床快速诊断试剂、食品安全检测试剂，违禁品快速检测，动物疾病防疫检测试剂，免疫诊断试剂、临床血液学和体液学检验试剂、微生物检验试剂、分子生物学检验试剂、临床生化试剂、有机试剂等众多领域，同时核心代理Panbio、FOCUS、Qiagen、IBL、CORTEZ、Fuller、Inbios、BinaxNOW、LumuQuick、日本富士、日本生研等多家有名诊断产品集团公司产品，致力于为商检单位、疾病预防控制中心、海关出入境检疫局、卫生防疫单位,缉毒系统，戒毒中心，检验检疫单位、生化企业、科研院所、医疗机构等机构与行业提供*、高品质的产品服务。此外，本公司还开展食品、卫生、环境、药品等多方面的第三方检测服务。）

主要用途：用于定量测定人血清、脑脊液或血浆中的麻疹抗体。

产品规格：96T/盒

存储条件：4-8℃

保质期：18个月

我司同时还提供、美国FOCUS、西班牙DIA、美国trinity等试剂盒：

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【产品介绍】

（1）潜伏期约10日（6～18天）。曾经接触过麻疹患儿或在潜伏期接受被动免疫者，可延至3-4周。在潜伏期内可有轻度体温上升。

（2）前驱期也称发疹前期，一般为3～4天。表现类似上呼吸道感染症状：①发热见于所有病例，多为中度以上发热；②咳嗽、流涕、流泪、咽部充血等，以眼症状突出，结膜发炎、眼睑水肿、眼泪增多、畏光、下眼睑边缘有一条明显充血横线（Stimson线），对诊断麻疹极有帮助。③麻疹黏膜斑，在发疹前24～48小时出现，为直径约1.0mm灰白色小点，外有红色晕圈，开始仅见于对着下臼齿的颊黏膜上，但在一天内很快增多，可累及整个颊黏膜并蔓延至唇部黏膜，黏膜疹在皮疹出现后即逐渐消失可留有暗红色小点；④偶见皮肤荨麻疹，隐约斑疹或猩红热样皮疹，在出现典型皮疹时消失；⑤部分病例可有一些非特异症状，如全身不适、食欲减退、精神不振等。但体温稍有下降。婴儿可有消化系统症状，呕吐、腹泻等。

（3）出疹期多在发热后3-4天出现皮疹。体温可突然升高至40～40.5℃，皮疹为稀疏不规则的红色斑丘疹，疹间皮肤正常，出疹顺序也有特点：始见于耳后、颈部、沿着发际边缘，24小时内向下发展，遍及面部、躯干及上肢，第3天皮疹累及下肢及足部。病情严重者皮疹常融合，皮肤水肿，面部水肿变形。大部分皮疹压之褪色，但亦有出现淤点者。全身有淋巴结肿大和脾肿大，并持续几周，肠系膜淋巴结肿大可引起腹痛、腹泻和呕吐。阑尾黏膜的麻疹病理改变可引起阑尾炎症状。疾病极期特别是高热时常有谵妄、激惹及嗜睡状态，多为一过性，热退后消失，与以后中枢神经系统合并症无关。此期肺部有湿性罗音，X线检查可见肺纹理增多。

(1) incubation period of about 10 days (6 to 18 days). Those who have been exposed to measles or passive immunization in the incubation period may be extended to 3-4 weeks. In the incubation period may have mild body temperature rise.

(2) Precursor Period also known as pre-eruption, usually 3 to 4 days. Symptoms similar to the upper respiratory tract infection: fever found in all cases, mostly moderate to moderate fever; cough, runny nose, tears, throat congestion, prominent in ocular symptoms, conjunctival inflammation, eyelid edema, increased tear, photophobia, The lower eyelid margin has an obvious congestion line (Stimson line), extremely helpful in the diagnosis of measles. Measles mucosa spots, 24 to 48 hours before the onset of rash appeared as a diameter of about 1.0mm gray dots, a red halo outside, beginning only seen in the buccal mucosa facing the lower molars, but soon increased in one day, Can affect the entire buccal mucosa and spread to the lip mucosa, mucosal rash disappears after the rash may appear dark red dots can be left; ④ occasional skin urticaria, vague rash or scarlet fever-like rash disappears in the presence of a typical rash ; ⑤ some cases may have some non-specific symptoms, such as general malaise, loss of appetite, lack of energy and so on. But the temperature dropped slightly. Infants may have digestive symptoms, vomiting, diarrhea and more.

(3) rash more than 3-4 days after the onset of fever rash. Body temperature can suddenly rise to 40 ~ 40.5 ℃, the rash is sparse irregular red rash, rash skin is normal, the order of the rash also has characteristics: first seen in the ear, neck, along the hairline edge, down within 24 hours Development, throughout the face, trunk and upper extremities, the third day of the rash involving the lower extremities and feet. Patients with severe rash often confluence, skin edema, facial edema deformation. Most of the skin rash pressure fade, but there are also those who have spots. Systemic lymph nodes and splenomegaly, and for several weeks, mesenteric lymph nodes can cause abdominal pain, diarrhea and vomiting. Appendectomy pathological changes in measles can cause appendicitis symptoms. Extreme disease especially during high fever, often delirium, irritability and lethargy state, mostly transient, disappear after the heat back and forth, has nothing to do with the subsequent central nervous system complications. This period of lung wet rales, X-ray examination showed increased lung texture.

【检测原理】

ELISA（酶联免疫吸附测定）是涉及的免疫学过程在抗体检测的感染领域尤其得到证实。该基于抗体和抗原的特异性相互作用的检测反应。至为此目的，使用赛润ELISA classic的微量滴定板的测试条传染性病原体特异性抗原在患者样品中的结合包被的抗体存在。 其他用碱性磷酸酶标记二抗检测由此形成的免疫复合物。 该酶催化a反应过程中，无色底物对硝基苯磷酸酯在有色产物中对硝基苯酚转化。 反应产物的信号强度正比于样品中的抗体浓度用光度法检测。

麻疹病毒IgG ELISA检测试剂盒

【试剂盒的组成】

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【公司名称】 广州健仑生物科技有限公司
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不受管制而迅速增殖的细胞通常会转变成良性肿瘤或恶性肿瘤。良性肿瘤不会扩散到身体其他部份，或是侵入别的组织，除非肿瘤的生长压迫到重要的器官，否则也不会影响生命。恶性肿瘤则会侵略其他器官，转移到身体其他部位而危害生命。
引起基因突变的物质被称为致癌物质，又以其造成基因损伤的方式可分为化学性致癌物与物理性致癌物。例如接触放射性物质，或是一些环境因子，例如，香烟、辐射、酒精。还有一些病毒可将本身的基因插入细胞的基因里中，激活癌基因。但突变也会自然产生，所以即使避免接触上述的致癌因子，仍然无法*预防癌症的产生。发生在生殖细胞的突变有可能传至下一代。
现知有1000多种化学物质具致癌作用，如黄曲霉素可致肝癌，香烟的燃烧物可致肺癌，亚硝胺可致食道癌。物理致癌因素中，放射线可致白血病，过强紫外照射和局部慢性刺激可致皮肤癌。病毒、寄生虫感染等生物因素可能与鼻咽癌、肝癌有一定关系。家族遗传、免疫水平、精神刺激、营养状态以及内分泌活动等因素亦对肿瘤的发生起重要作用。尤其是精神因素与癌症的近来倍受重视。
生活方式的影响
生活方式对于癌症发生确实是有影响，例如香烟、饮食、运动、酒精、晒太阳以及性病等。
zui近几十年的研究中，zui为确定的发现就是抽烟和癌症间密切的相关性，许多流行病学研究也已经证实这样的关系。根据美国的数据显示，随着吸烟人数增加，肺癌的死亡率急剧升高。
同时有越来越多的研究显示，癌症发生也和体内褪黑激素的量相关，当需要长时间待在明亮的环境下，例如晚班的工人。或是睡眠时间较短的人，褪黑激素表现量也会偏低，而癌症的发病率较高。
癌症的传染
有些并非发生在人类的癌症可能能经由传染而引起，例如发生于狗的史狄可氏肉瘤（Sticker's sarcoma）。有病患接受细菌，由于移植器官中带有肿瘤，结果得到癌症。这是目前已知较类似经由传染而得的例子。
癌症的遗传

Unregulated and rapidly proliferating cells often turn into benign or malignant tumors. Benign tumors do not spread to other parts of the body, or invade other tissues, and do not affect life unless the growth of the tumor compresses into vital organs. Malignant tumors will invade other organs, transfer to other parts of the body and endanger life.
Substance causing mutations are called carcinogens, but also its way to cause genetic damage can be divided into chemical carcinogens and physical carcinogens. Such as exposure to radioactive material, or some environmental factors, such as cigarettes, radiation, and alcohol. Still others can insert their own genes into the cell's genes and activate oncogenes. But mutations also occur naturally, so even if you avoid contact with these oncogenic factors, you still can not compley prevent cancer. Mutations that occur in germ cells are likely to reach the next generation.
Now known to have more than 1,000 kinds of chemical substances with carcinogenic effects, such as aflatoxin can cause liver cancer, the combustion of cigarettes can cause lung cancer, nitrosamines can cause esophageal cancer. Among the physical carcinogenic factors, radiation can cause leukemia, too strong UV irradiation and local chronic irritation can cause skin cancer. Viruses, parasitic infections and other biological factors may be related to nasopharyngeal carcinoma, liver cancer have a certain relationship. Family genetic, immune levels, mental stimulation, nutritional status and endocrine activities and other factors also play an important role in tumorigenesis. In particular, the link between mental factors and cancer has drawn much attention recently.
The impact of lifestyle
Lifestyles do have an impact on cancer, such as cigarettes, diet, exercise, alcohol, sunbathing, and sexually transmitted diseases.
The most definitive finding in recent decades of research is the close correlation between smoking and cancer, and many epidemiological studies have confirmed this relationship. According to the U.S. data, as the number of smokers increases, the mortality rate of lung cancer has risen sharply.
In the meantime, more and more studies show that the incidence of cancer is also related to the amount of melatonin in the body when it takes a long time to stay in a bright environment, such as night shift workers. Or people who sleep for a short time, melatonin performance will be low, while the incidence of cancer is higher.
Infection with cancer
Some cancers that are not in humans can be caused by infection, such as Sticker's sarcoma in dogs. Patients receive the bacteria, and as a result of the tumor in the transplanted organ, the result is cancer. This is an example known to be more contagious now.
Genetics of cancer