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【公司名称】 广州健仑生物科技有限公司
【市场部】    杨永汉

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【腾讯  】 2042552662
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-103室

利用小鼠朊病毒疾病的模型，研究人员确定这些新生神经元产生的时间进程，以及它们如何融入大脑回路中。虽然这种自我修复机制能够有效维持疾病早期和中间阶段的神经功能，但是在更高级的阶段中却无法维持。这突出一个为了保护有益增强神经发生的影响的潜在干预治疗的时间窗口。
戈麦斯 - 尼古拉博士说：“这项研究显示，大脑的潜能有助于协调自我修复反应。继续这方面的研究开辟新的途径，确定哪些特殊信号有助于促进神经发生反应的增加，专注于神经发生作为一种促进缺失神经元再生的治疗方法。”
这项研究发表于《大脑》杂志上，由欧盟第七框架计划和医学研究理事会(MRC)资助。
已知由大脑中的海马体协调学习和记忆能力。在诞生之前，大脑的大部分已经发育完毕。此后还要经历两个发育高峰时期，一个是儿童期，一个是青春期，这两个阶段大脑发育快速。在过去20年间，研究证实，成人的神经再生主要发生在海马体中。
该研究通过一个动物模型发现，核受体TLX基因过量表达时，试验对象聪明且学习起来更快，另外所获得的信息能持续得更持久。

Using a model of mouse prion disease, researchers determine the timing of these newborn neurons and how they integrate into the brain's circuitry. Although this self-healing mechanism can effectively maintain the neurological function of the early and middle stages of the disease, it can not be maintained at a more advanced stage. This highlights a time window for potential interventions to protect the beneficial effects of neurogenesis.
Dr. Gomez-Nicola said: "This study shows that the brain's potential helps to coordinate self-healing reactions." Continuing studies in this area have opened up new avenues to determine which particular signals contribute to promoting an increased neurogenic response , Which focuses on neurogenesis as a treatment for de novo neuron regeneration. "
The study, published in the journal Brain, is funded by the EU's Seventh Framework Program and the Medical Research Council (MRC).
It is known that the hippocampus in the brain coordinates the learning and memory abilities. Before birth, much of the brain has been developed. There are two more developmental periods to follow, one in childhood and one in adolescence, during which time the brain develops rapidly. In the past 20 years, studies have confirmed that adult nerve regeneration occurs mainly in the hippocampus.
The study, based on an animal model, found that when the nuclear receptor TLX gene is overexpressed, subjects are smart and learn faster, and the information they receive lasts longer.