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【公司名称】 广州健仑生物科技有限公司
【市场部】    杨永汉

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美国纽约大学医学院和中国北京大学深圳研究生院的研究人员在小鼠的一项研究中表明，睡眠可巩固记忆，而它是通过促进脑中新的突触的生长来做得这一点的。相关文章发表于2014年6月6日的《science》杂志上。
科学家们长期以来就知道，睡眠可帮助增进学习及记忆，尽管这一过程是如何发挥作用的则一直晦暗不明，尤其是当睡眠被显示会减少脑中的突触数或神经连接时。(寻找睡眠与记忆之间有某种的研究人员会期待看到睡眠时突触数会有所增加。)
Guang Yang及其同事zui近在该领域中取得了进展;他们证明，教小鼠学习一种新的运动技能——如在某根杆子顶部保持平衡——会引起它们脑中新的树突棘的形成(树突棘的数目与神经突触数是相关的)。这提示，在哺乳类动物脑中的突触变化是学习的基础。
如今，为了探索睡眠是否会影响突触变化，Yang等人用一种技术来观看活体小鼠运动皮层中的树突棘。他们训练小鼠学习不同的技能。有些小鼠可在学习后马上得到睡眠;另外一些小鼠则要经历一段8小时的睡眠剥夺时间。睡眠可引起新树突棘数的增加。剥夺睡眠则适得其反。实际上，睡眠剥夺的影响是如此之强，它能压制额外训练的效果;即使当睡眠剥夺小鼠得到对某技能的更严格的训练，但它们仍然比那些得到休息的对等小鼠所长出的新突触棘要少。

Researchers at the New York University School of Medicine in the United States and the Shenzhen Graduate School of Peking University in China have shown in a study of mice that sleep can consolidate memory by doing this by promoting the growth of new synapses in the brain. A related article was published in "science" magazine on June 6, 2014.
Scientists have long known that sleep helps to improve learning and memory, though the process of how it works has been obscure, especially when sleep is shown to reduce the number of synapses or neural connections in the brain. (Researchers looking for a connection between sleep and memory expect to see an increase in the number of synapses when they sleep.)
Guang Yang and colleagues recently made progress in the field; they demonstrated that teaching mice to learn a new motor skill - such as balancing on the top of a pole - can cause new dendrites in their brains (The number of dendritic spines is related to the number of synapses). This suggests that synaptic changes in the mammalian brain are the foundations of learning.
Now, to explore whether sleep affects synaptic changes, Yang et al. Used a technique to see dendritic spines in the motor cortex of living mice. They train mice to learn different skills. Some mice sleep immediay after they learn; others have an 8-hour sleep deprivation period. Sleep can cause an increase in the number of new dendrites. Deprivation of sleep is counterproductive. In fact, the effect of sleep deprivation is so strong that it can suppress the effects of additional training; even when sleep-deprived mice receive more rigorous training in a particular skill, they are still more likely than their peers who are rescued The new synaptic out less.