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乙型流感IgM ELISA抗原免疫层析法检测试纸
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乙型流感IgM ELISA抗原免疫层析法检测试纸
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【公司名称】 广州健仑生物科技有限公司
【市场部】 杨永汉
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【腾讯 】 2042552662
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-103室
目前,人类对短期进入微重力环境适应过程中的有关生物学机制有些初步了解,长期(数年)在空间生活的影响还有待进一步认识。细胞是构成生命有机体的基本结构和功能的单位,不管在失重条件下人体在生理等方面表现如何,微重力环境下产生的所有效应均是单细胞本身或细胞间相互产生反应的zui高形式。有名的细胞生物学家B.Wilson早在1925年就指出,生命科学问题的答案必定从细胞中去寻找。开展空问细胞科学研究是人类认识及征服太空的必由之路。但是细胞的生长需要一定的条件,包括温度、湿度、氧气、养料、pH等,它们有复杂的代谢需要,并且对器皿壁的相互作用和流体应力十分敏感,尤其对纤弱的哺乳动物细胞更是如此,因而空间细胞培养的研究是开展空间细胞生物学研究的基础与前提条件。
近年来,生物医学界报道了许多成功的临床应用例子,如单克隆抗体、基因工程重组蛋白、细胞因子、疫苗等,这些生物技术产品都有很高的经济和社会效益,往往涉及动、植物细胞的大规模培养技术。微重力环境为细胞培养提供许多有利之处,由于空间无沉降无对流的特性,物质可以均匀悬浮,细胞不会因重力场的影响而沉降堆积在一个表面,这对于进行细胞的高密度培养,提高介质的利用率和单位容积的产量,减少其它蛋白的污染都是有利的;并且空间纯净的培养环境,获得更加均一、更加纯净的物质的潜力,防止污染等,为空问制药带来了许多有利之处;特别是近些年来报道空间细胞的生物合成和分泌作用发生改变,某些重要蛋白质的产量和品质可以提高;在微重力下细胞具有三维生长的潜能。因而空间细胞培养是目前看好的三大空间生物技术(蛋白质结晶,细胞培养,生物分离)之一,也是空间生物加工的重要组成部分。国外在空间细胞培养方面所用的装置在70年代初期一般都是由小的培养容器组成,但是细胞的生长需要一定的条件,包括温度、湿度、氧气、养料、pH等,它们有复杂的代谢需要,并且对器皿壁的相互作用和流体应力十分敏感,尤其对纤弱的哺乳动物细胞更是如此,因而空间细胞培养的研究是开展空间细胞生物学研究的基础与前提条件。
At present, human beings have some initial understanding about the biological mechanism in the adaptation process of short-term access to the micro-gravity environment. The impact of long-term (years) living in space needs to be further recognized. Cells constitute the basic structure and function of living organisms. Regardless of their physiology under conditions of weightlessness, all the effects produced under the micro-gravity environment are the highest forms of single cell or cell-cell interactions. Famous cell biologist As early as 1925, Wilson pointed out that the answer to the life sciences problem must be sought from the cell. It is the only way for human beings to understand and conquer space in order to carry out scientific research in space-based cells. However, the growth of cells requires certain conditions, including temperature, humidity, oxygen, nutrients, pH, etc., which have complex metabolic requirements and are very sensitive to vessel wall interactions and fluid stress, especially to delicate mammalian cells Thus, the study of space cell culture is the basis and prerequisite for the study of space cell biology.
In recent years, the biomedical community reported many successful clinical application examples, such as monoclonal antibodies, recombinant proteins, cytokines, vaccines, these biotechnology products have high economic and social benefits, often involving animals and plants Large-scale cell culture technology. Microgravity environment for cell culture provides many advantages, due to space-free non-convective convection, the material can be uniformly suspended, the cell will not be deposited due to the influence of the gravitational field accumulation in a surface, which for high-density cell culture, It is advantageous to increase the utilization rate of the medium and the yield per unit volume, and to reduce the pollution of other proteins; and the space-pure culture environment, the potential of obtaining a more homogeneous and pure substance, prevention of pollution and the like, Many advantages. Especially in recent years, it has been reported that the biosynthesis and secretion of space cells have changed, the yield and quality of some important proteins can be improved, and the cells have the potential of three-dimensional growth under microgravity. Therefore, the space cell culture is one of the three major space biotechnology (protein crystallization, cell culture and biological separation) currently favored by the world and is also an important part of the biological processing of space. In the early 1970s, the devices used in the overseas cell culture generally consisted of small culture vessels, but cell growth required certain conditions including temperature, humidity, oxygen, nutrients, pH, etc., which required complex metabolic needs , And is very sensitive to the vessel wall interaction and fluid stress, especially to the delicate mammalian cells. Therefore, the research of space cell culture is the basis and precondition for the research of space cell biology.